Eugenell Mae Lopez

Microbiota- and diet-specific T cells become Tregs by default

The paper shows that T cells specific for microbiota and diet antigens predominantly become regulatory T cells (iTregs) in the gut, with effector responses emerging only under specific inflammatory and genetic conditions.

Ecology and engineering to modify the bile acid output of a defined microbial community

The paper shows that modifying microbial community composition, specifically overexpressing bile acid metabolic genes in Lactobacillus strains, can alter bile acid pool size and composition in mice.

A single-strain dropout screen reveals mechanistic links between microbial ecology and metabolism

The paper uses a single-strain dropout screen in a defined microbial community to show how removing specific strains affects community composition and metabolic output.