Jamie Blum

Intestinal uptake, set by protein solubility and goblet versus M cell sampling, limits how strongly different zein preparations induce antigen-specific intestinal T cells in mice.

The paper shows that T cells specific for microbiota and diet antigens predominantly become regulatory T cells (iTregs) in the gut, with effector responses emerging only under specific inflammatory and genetic conditions.

The paper identifies seed storage protein epitopes as targets of intestinal regulatory T cells that modulate immune responses to dietary antigens.

This study shows that oxybutynin rescues proliferative capacity and metabolic function in Complex III-defective mitochondrial progenitor cells.

This study identifies PDGFRβ signaling as a regulator of myocyte fusion and muscle regeneration, showing that its suppression enhances muscle repair and myofiber size.