Author

Aishan Zhao

Stanford UniversityORCID 0000-0002-9010-7981Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Michael Andrew FischbachiD· 4 shared Masahiko Terasaki· 3 shared Allison M. WeakleyiD· 2 shared Anne Trinh· 2 shared Ashley V. Cabrera· 2 shared Brian C. DeFeliceiD· 2 shared Djenet BousbaineiD· 2 shared Eugenell Mae Lopez· 2 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersMicrobiology

Michael Andrew FischbachORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Enzymatic attachment of antigens to probe immune modulation by skin commensals

Djenet Bousbaine, Pranav V. Lalgudi, Katherine D. Bauman, Eunice Tsang, Tam T.D. Nguyen, Anchaleena James, Miki Chiang, Aishan Zhao, Masahiko Terasaki, Joyce M. Swenson, Anne Trinh, Michael A. Fischbach

This study uses recombinant sortase to attach antigens to Gram-positive bacteria, demonstrating a non-genetic method to induce protective immunity in vivo.

bioRxiv · Nov 3, 2026 · PreprintImmunology

Microbial mechanistic requirements for eliciting a topical and intranasal immune response

Katherine D. Bauman, Pranav V. Lalgudi, Djenet Bousbaine, Anchaleena James, Miki L. Chiang, Tam T. D. Nguyen, Joyce M. Swenson, Eunice Tsang, H J Kim, Felicitas Ruiz, Naveen Jasti, Zachary Jones, David B. Li, Annie T Nguyen, Anne Trinh, , Michael Andrew Fischbach

This study demonstrates that Staphylococcus epidermidis can be engineered to elicit potent immune responses when applied topically or intranasally, with nasal colonization inducing stronger systemic and mucosal immunity.

bioRxiv · Jul 16, 2026 · PreprintMicrobiology

Ecology and engineering to modify the bile acid output of a defined microbial community

Xianfeng Zeng, Xiandong Meng, Allison M. Weakley, Kelsey E. Jarrett, Steven Kyle Higginbottom, Eugenell Mae Lopez, Ashley V. Cabrera, Ira J. Gray, Brian C. DeFelice, Masahiko Terasaki, Rochelle Lai, Madelaine C. Brearley-Sholto, Aishan Zhao, Kerrigan R Hall, Mikhail Levia, , Michael Andrew Fischbach

The paper shows that modifying microbial community composition, specifically overexpressing bile acid metabolic genes in Lactobacillus strains, can alter bile acid pool size and composition in mice.

bioRxiv · May 25, 2026 · PreprintMicrobiology

A single-strain dropout screen reveals mechanistic links between microbial ecology and metabolism

Xianfeng Zeng, Xiandong Meng, Allison M. Weakley, Steven Kyle Higginbottom, Eugenell Mae Lopez, Ashley V. Cabrera, Ira J. Gray, Brian C. DeFelice, Masahiko Terasaki, Aishan Zhao, Kerrigan R Hall, Mikhail Levia, Jeanette Arreola, Michael Andrew Fischbach

The paper uses a single-strain dropout screen in a defined microbial community to show how removing specific strains affects community composition and metabolic output.

bioRxiv · May 25, 2026 · PreprintMicrobiology