Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death
Breanna Lam, Kathrin M. Kajderowicz, Heather R. Keys, Julian M. Roessler, Tara G. Thakurta, Evgeni M. Frenkel, Adina Kirkland, Punam Bisht, Mohamed A. El-Brolosy, Rudolf Jaenisch, George W. Bell, Jonathan S. Weissman, Eric C. Griffith, Siniša Hrvatin
This study identifies GPX4 as a conserved suppressor of cold-induced cell death through multi-species CRISPR screens in hibernators and non-hibernators.
bioRxiv · Jul 25, 2024 · PreprintCell Biology