Author

Kathrin M Kajderowicz

Whitehead Institute for Biomedical ResearchORCID 0000-0002-5541-4150Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 4 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Jonathan S. WeissmaniD· 3 shared George W. BelliD· 2 shared James C. Cameron· 2 shared Yuancheng Ryan LuiD· 2 shared Adina Kirkland· 1 shared Alexander TyshkovskiyiD· 1 shared Andrea ArmaniiD· 1 shared Andrew L. CangelosiiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Jonathan S. WeissmanORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A genome-scale ORF screen for resilience factors that protect the RPE and restore vision in aged mice

Yuancheng Ryan Lu, Han Shen, Kathrin M Kajderowicz, 艾家和, Yi Hua Chen-Neumann, Yan Hu, Alexander Tyshkovskiy, Qiannuo Lou, Tianwei Dong, Louisa Grauvogel, Zhaoyi Chen, James C. Cameron, Ximeng Li, 新多朗白濱, Michael Bligh, , Jonathan S. Weissman

The paper identifies resilience factors in aged mice using a genome-scale ORF screen, finding NKX2-5 variants that restore vision and reduce frailty.

bioRxiv · Sep 30, 2026 · PreprintGenetics

Atlas of Lysosomal Aging Reveals a Molecular Clock of Storage Disorder-Associated Metabolites

Anna M. Puszynska, Thao Phuong Nguyen, Andrew L. Cangelosi, Andrea Armani, Justin M. Roberts, Kristin A. Singh, James C. Cameron, Tenzin Tseyang, Grace Y. Liu, Steven Lai, Hans‐Georg Sprenger, Jason Yang, William N. Colgan, Jibril F. Kedir, Kathrin M Kajderowicz, , Jonathan S. Weissman

The paper constructs a multi-tissue lysosomal metabolite atlas in mice, revealing age-related accumulation of glycerophosphodiesters and cystine, linked to lysosomal storage disorders, and shows caloric restriction mitigates these changes in some tissues.

bioRxiv · Sep 25, 2025 · PreprintCell Biology

Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death

Breanna Lam, Kathrin M. Kajderowicz, Heather R. Keys, Julian M. Roessler, Tara G. Thakurta, Evgeni M. Frenkel, Adina Kirkland, Punam Bisht, Mohamed A. El-Brolosy, Rudolf Jaenisch, George W. Bell, Jonathan S. Weissman, Eric C. Griffith, Siniša Hrvatin

This study identifies GPX4 as a conserved suppressor of cold-induced cell death through multi-species CRISPR screens in hibernators and non-hibernators.

bioRxiv · Jul 25, 2024 · PreprintCell Biology

Spatiotemporal patterns of neuronal subtype genesis suggest hierarchical development of retinal diversity

Emma R. West, Sylvain W. Lapan, ChangHee Lee, Kathrin M Kajderowicz, Xihao Li, Constance L. Cepko

The paper maps the spatiotemporal development of bipolar interneuron subtypes in the mammalian retina, revealing a hierarchical model of subtype genesis through ordered birthdates and oscillatory waves.

Cell Reports · Jan 1, 2022Peer-reviewedDevelopmental Biology