F. D. Finkelman

Microbiota epigenetically direct tuft cell differentiation to control type 2 immunity

This study shows that butyrate-producing bacteria epigenetically control tuft cell differentiation via HDAC3, influencing type 2 immunity and helminth responses.

The Hdc GC box is critical for Hdc gene transcription and histamine-mediated anaphylaxis

This study identifies the Hdc GC box as essential for Hdc gene transcription, histamine synthesis, and anaphylaxis in mice and human mast cells.