Author

M. R. Frey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Waddell· 2 shared E. B. Bucar· 2 shared M. A. Schumacher· 2 shared A. Fong· 1 shared C. Potter· 1 shared C. Y. Liu· 1 shared D. Almohazey· 1 shared D. Warburton· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

A. Waddell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dysregulation of γδ intraepithelial lymphocytes precedes Crohn's disease-like ileitis

W. Xu, N. B. Golovchenko, A. Fong, S. Achi, E. B. Bucar, K. J. Vidmar, L. Zhang, M. R. Frey, I. Prinz, T. T. Pizarro, G. Kollias, K. L. Edelblum

This study identifies dysregulation of γδ intraepithelial lymphocytes (IELs) before the onset of Crohn's disease-like ileitis in a mouse model.

bioRxiv · Aug 31, 2023Immunology

Microbiota epigenetically direct tuft cell differentiation to control type 2 immunity

E. M. Eshleman, T. Rice, C. Potter, A. Waddell, S. Hashimoto-Hill, V. Woo, S. Field, L. Engleman, M. A. Schumacher, M. R. Frey, L. A. Denson, F. D. Finkelman, T. Alenghat

This study shows that butyrate-producing bacteria epigenetically control tuft cell differentiation via HDAC3, influencing type 2 immunity and helminth responses.

bioRxiv · Mar 2, 2023Immunology

Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33.

M. A. Schumacher, J. J. Hsieh, C. Y. Liu, K. L. Appel, A. Waddell, D. Almohazey, K. Katada, J. K. Bernard, E. B. Bucar, S. Gadeock, K. M. Maselli, M. K. Washington, T. C. Grikscheit, D. Warburton, M. J. Rosen, M. R. Frey

This study shows that Sprouty2 restricts intestinal tuft and goblet cell numbers via GSK3β-mediated IL-33 expression, with implications for inflammatory bowel disease.

bioRxiv · Mar 9, 2020Physiology