P. Oliveira

Unveiling the Mechanisms to Bypass KRAS Inhibition: In Vitro Insights into the Influence of Fibroblast-Secretome

This study investigates how fibroblast-secreted factors promote KRAS-independent stemness in KRAS-mutant CRC cells, revealing a mechanism by which the tumor microenvironment contributes to resistance to KRAS inhibition.

High-Dimensional Imaging of Vestibular Schwannoma Reveals Distinctive Immunological Networks Across Histomorphic Niches in NF2-related Schwannomatosis

This study uses imaging mass cytometry to analyze spatial immunological differences in vestibular schwannomas from NF2 SWN patients, revealing niche-dependent T-cell regulation.

Structural and functional characterization of the NF-κB-targeting toxin AIP56 from Photobacterium damselae subsp. piscicida reveals a novel mechanism for membrane interaction and translocation

Resistance to EGFR inhibitors in lung cancer occurs through horizontal transfer and is associated with increased caveolins expression

The Amidella clade in Europe (Amanita Pers., Basidiomycota: Amanitaceae): clarification of the contentious Amanita valens and the importance of taxon-specific PCR primers for identification

The paper clarifies the taxonomy of Amanita valens and introduces a new variety, Amanita pseudovalens var. tartessiana, using molecular markers to aid identification.

Epithelial-mesenchymal plasticity induced by discontinuous exposure to TGFβ1 promotes tumour growth

The paper shows that discontinuous TGFβ1 exposure induces EMT/MET transitions in EpH4 cells, leading to RE-cells with molecular and functional heterogeneity that promotes tumour growth.

A Stomata Classification and Detection System in Microscope Images of Maize Cultivars

This paper proposes a deep learning-based system for automatic stomata classification and detection in maize cultivar microscope images, achieving 97.1% accuracy.

Development of a novel allograft model of prostate cancer: a new tool to inform clinical translation

This paper develops a novel allograft model of high-risk prostate cancer that mimics human disease features and responds to radiotherapy.

Host range and genetic plasticity explain the co-existence of integrative and extrachromosomal mobile genetic elements

The paper compares integrative and extrachromosomal mobile genetic elements to explain their co-existence through differences in genetic plasticity and host range.