Capsule protects against intracellular killing and enables vascular endothelial cell translocation during invasive pneumococcal disease
T. Brissac, E. Martinez, K. L. Kruckow, A. N. Riegler, F. Ganaie, H. Im, S. Bakshi, N. M. Arroyo-Diaz, B. Spencer, J. S. Saad, M. H. Nahm, C. J. Orihuela
This study shows that pneumococcal capsule protects bacteria from oxidative stress in host cells and enhances disease severity by promoting intracellular survival and translocation.
bioRxiv · Feb 10, 2021 · PreprintMicrobiology