Author

A. N. Riegler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. J. Orihuela· 2 shared A. S. Jureka· 1 shared B. Spencer· 1 shared C. M. Petit· 1 shared E. Martinez· 1 shared F. Ganaie· 1 shared H. Im· 1 shared J. Brand· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

C. J. Orihuela

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Author profile →

2 papers

Recent·Most cited

Capsule protects against intracellular killing and enables vascular endothelial cell translocation during invasive pneumococcal disease

T. Brissac, E. Martinez, K. L. Kruckow, A. N. Riegler, F. Ganaie, H. Im, S. Bakshi, N. M. Arroyo-Diaz, B. Spencer, J. S. Saad, M. H. Nahm, C. J. Orihuela

This study shows that pneumococcal capsule protects bacteria from oxidative stress in host cells and enhances disease severity by promoting intracellular survival and translocation.

bioRxiv · Feb 10, 2021 · PreprintMicrobiology

Influenza-induced oxidative stress sensitizes lung cells to bacterial toxin-mediated necroptosis

N. Gonzalez-Juarbe, A. N. Riegler, A. S. Jureka, R. P. Gilley, J. Brand, J. E. Trombley, N. R. Scott, P. H. Dube, C. M. Petit, K. S. Harrod, C. J. Orihuela

This paper shows that influenza virus increases lung cell sensitivity to bacterial toxin-induced necroptosis through oxidative stress, suggesting necroptosis inhibitors as potential treatments for severe infections.

bioRxiv · Feb 20, 2020Microbiology