Author

M. Graewert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Assay:structural biology· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

D. I. Svergun· 4 shared A. Gruzinov· 1 shared A. J. R. Heck· 1 shared A. Sartbaeva· 1 shared A. Sponga· 1 shared A. Wahid· 1 shared A. Watts· 1 shared A.-C. Gavin· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersBiochemistry

D. I. Svergun

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Author profile →

4 papers

Recent·Most cited

Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF

I. Corbeski, X. Guo, B. V. Eckhardt, D. Fasci, W. W. Wiegant, M. Graewert, K. Vreeken, H. Wienk, D. I. Svergun, A. J. R. Heck, H. van Attikum, R. Boelens, T. K. Sixma, F. Mattiroli, H. van Ingen

The paper shows that the acidic domain of APLF assembles histone octamers and deposits them onto DNA to form nucleosomes.

bioRxiv · Dec 24, 2021Biochemistry

Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats

S. Sajko, I. Grishkovskaya, J. Kostan, M. Graewert, K. Setiawan, L. Truebestein, K. Niedermuller, C. Gehin, A. Sponga, M. Puchinger, A.-C. Gavin, T. Leonard, D. I. Svergun, T. K. Smith, B. C. Morriswood, K. Djinovic-Carugo

This study investigates MORN repeat proteins, revealing they are protein-protein interaction modules rather than lipid-binding modules, based on structural and functional analyses of TbMORN1 and homologs.

bioRxiv · Jun 23, 2020Biochemistry

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2

T. F. Custodio, H. Das, D. J. Sheward, L. Hanke, S. Pazicky, J. Pieprzyk, M. Sorgenfrei, M. Schroer, A. Gruzinov, C. Jeffries, M. Graewert, D. I. Svergun, N. Dobrev, K. Remans, M. Seeger, , C. Löw

This study isolates and characterizes synthetic nanobodies that neutralize SARS-CoV-2, identifying Sb23 with high affinity and neutralization activity.

bioRxiv · Jun 23, 2020Biophysics

Utilisation of staphylococcal immune evasion protein Sbi as a novel vaccine adjuvant

Y. Yang, C. Back, M. Graewert, A. Wahid, H. Denton, R. Kildani, J. Paulin, K. Woerner, W. Kaiser, D. I. Svergun, A. Sartbaeva, A. Watts, K. Marchbank, J. M. van den Elsen

This paper demonstrates that the Staphylococcal protein Sbi can be used as a vaccine adjuvant by promoting natural opsonisation of antigens with C3 fragments, enhancing immune responses.

bioRxiv · Sep 10, 2018Biochemistry