An intranasal lentiviral booster broadens immune recognition of SARS-CoV-2 variants and reinforces the waning mRNA vaccine-induced immunity that it targets to lung mucosa
B. Vesin, J. Lopez, A. Noirat, P. Authie, I. Fert, F. Le Chevalier, F. Moncoq, K. Nemirov, C. Blanc, C. Planchais, H. Mouquet, F. Guinet, D. Hardy, C. Gerke, F. Anna, , P. Charneau
This study shows an intranasal lentiviral booster enhances and broadens immune response to SARS-CoV-2 variants and improves waning mRNA vaccine immunity in the lungs.
bioRxiv · Jan 30, 2022 · PreprintImmunology