Author

C. Blanc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

A. Noirat· 3 shared B. Vesin· 3 shared F. Anna· 3 shared F. Guinet· 3 shared F. Moncoq· 3 shared J. Lopez· 3 shared K. Nemirov· 3 shared L. MAJLESSI· 3 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

A. Noirat

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus

I. Fernandez, N. Saunders, S. Duquerroy, W. H. Bolland, A. Arbabian, E. Baquero, C. Blanc, P. Lafaye, A. Haouz, J. Buchrieser, O. Schwartz, F. A. Rey

This study determines the structure of HKU1-CoV receptor binding domain in complex with TMPRSS2, identifying key residues for host tropism and revealing the structural basis of TMPRSS2 activation.

bioRxiv · Feb 21, 2024Biochemistry

Co-segregation of recombinant chromatids maintains genome-wide heterozygosity in an asexual nematode

C. Blanc, N. saclier, E. Le Faou, L. Marie-Orleach, E. Wenger, C. Diblasi, S. Glemin, N. Galtier, M. Delattre

The study shows that genome-wide heterozygosity in the asexual nematode Mesorhabditis belari is maintained through directed assortment of recombinant chromatids during female meiosis.

bioRxiv · Mar 17, 2023Evolutionary Biology

An intranasal lentiviral booster broadens immune recognition of SARS-CoV-2 variants and reinforces the waning mRNA vaccine-induced immunity that it targets to lung mucosa

B. Vesin, J. Lopez, A. Noirat, P. Authie, I. Fert, F. Le Chevalier, F. Moncoq, K. Nemirov, C. Blanc, C. Planchais, H. Mouquet, F. Guinet, D. Hardy, C. Gerke, F. Anna, , P. Charneau

This study shows an intranasal lentiviral booster enhances and broadens immune response to SARS-CoV-2 variants and improves waning mRNA vaccine immunity in the lungs.

bioRxiv · Jan 30, 2022 · PreprintImmunology

Full Brain and Lung Prophylaxis against SARS-CoV-2 by Intranasal Lentiviral Vaccination in a New hACE2 Transgenic Mouse Model or Golden Hamsters

M.-W. Ku, P. Authie, M. Bourgine, F. Anna, A. Noirat, F. Moncoq, B. Vesin, F. Nevo, J. Lopez, P. Souque, C. Blanc, S. Chardenoux, I. Lafosse, D. Hardy, K. Nemirov, , P. Charneau

This study shows that an intranasal lentiviral vaccine protects both the respiratory and central nervous systems against SARS-CoV-2 in a new hACE2 transgenic mouse model.

bioRxiv · Feb 3, 2021 · PreprintMicrobiology

Intranasal Vaccination with a Lentiviral Vector Strongly Protects against SARS-CoV-2 in Mouse and Golden Hamster Preclinical Models

M.-W. Ku, M. Bourgine, P. Authie, J. Lopez, K. Nemirov, F. Moncoq, A. Noirat, B. Vesin, F. Nevo, C. Blanc, P. Souque, H. Tabbal, E. Simon, M. Le Dudal, F. Guinet, , P. Charneau

This study shows that intranasal vaccination with a lentiviral vector encoding the SARS-CoV-2 Spike protein provides strong protection against SARS-CoV-2 in mice and golden hamsters by reducing viral load and inflammation.

bioRxiv · Jul 21, 2020 · PreprintImmunology