Perivascular fibroblasts locally regulate the vasomotor dynamics of pial arterioles
Stephanie Karas, Elisabeth Harmon, Orla Bonnar, Bradley T. Pawlikowski, Danielle A Jeffrey, Laura M Munoz, Fiona Lake, Maria J Sosa Ibarra, Cara D. Nielson, Fabrice Dabertrand, Julie A. Siegenthaler, Andy Y. Shih, Stephanie K. Bonney
This study identifies perivascular fibroblasts as regulators of cerebral vasomotion and cerebrospinal fluid movement through calcium dynamics and Gq signaling.
bioRxiv · Sep 18, 2026 · PreprintNeuroscience