Cara D. Nielson

This study identifies perivascular fibroblasts as regulators of cerebral vasomotion and cerebrospinal fluid movement through calcium dynamics and Gq signaling.

This paper develops a closed-skull mouse model for repetitive mild traumatic brain injury using a custom weight-drop apparatus and evaluates behavioral and neuroinflammatory outcomes.

The paper shows that capillary injury and regression lead to sustained vasoconstriction in upstream vessels, reducing blood flow in both injured and uninjured regions of the microvascular network.

This study shows that pericyte loss in aged brains leads to capillary dilation, flow heterogeneity, and structural disruption, highlighting pericyte remodeling as a therapeutic target.