Danielle A Jeffrey

Perivascular fibroblasts locally regulate the vasomotor dynamics of pial arterioles

This study identifies perivascular fibroblasts as regulators of cerebral vasomotion and cerebrospinal fluid movement through calcium dynamics and Gq signaling.

Estrogen regulates myogenic tone in hippocampal arterioles by enhanced basal release of nitric oxide and endothelial SKCa channel activity

This study shows estrogen reduces myogenic tone in hippocampal arterioles by increasing nitric oxide release and endothelial SKCa channel activity in female mice.

VasoTracker 2: An Open-source Platform for Quantitative Analysis of Vascular Reactivity and Function

VasoTracker 2 provides open-source software and low-cost hardware for analyzing vascular reactivity and function across multiple imaging modalities.

Impact of Serum Circulating Factors and PDE5 Inhibitor Therapy on Cardiomyocyte Metabolism in Single Ventricle Heart Disease

This study investigates how serum factors and PDE5 inhibitor therapy affect cardiomyocyte metabolism in single ventricle heart disease, finding that PDE5 inhibitors improve mitochondrial function and metabolic intermediates.

Microglia are not required for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism

The paper investigates the role of microglia in maintaining blood-brain barrier properties in health and finds that microglia are not required, but PLX5622 treatment affects endothelial cholesterol metabolism.