Author

Florence Stoffel

ETH Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Paolo ArosioiD· 2 shared Ana I. Benítez‐MateosiD· 1 shared Andreas M. KüffneriD· 1 shared Karolína Mrzílková· 1 shared Lenka FaltovaiD· 1 shared Marcell PappiD· 1 shared Marco A. BühleriD· 1 shared Marcos Gil-GarcíaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Paolo ArosioORCID

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2 papers

Recent·Most cited

Engineering nanocondensate formation through sequence composition and patterning

Timo N. Schneider, Florence Stoffel, Marco A. Bühler, Karolína Mrzílková, Milad Radiom, Paolo Arosio

This paper designs peptides that form stable nanocondensates by combining computational methods with experimental validation, revealing molecular mechanisms that control condensate size.

bioRxiv · Feb 19, 2026 · PreprintBiophysics

Enhancement of Enzymatic Activity by Biomolecular Condensates through pH Buffering

Florence Stoffel, Marcell Papp, Marcos Gil-García, Andreas M. Küffner, Ana I. Benítez‐Mateos, Raphaël P. B. Jacquat, Nicola Galvanetto, Lenka Faltova, Paolo Arosio

This study shows that biomolecular condensates enhance enzymatic activity by buffering pH, allowing enzymes to function effectively in acidic conditions and enabling pH-dependent cascade reactions.

Nature Communications · Jul 10, 2025Peer-reviewedBiochemistry