Enhancement of Enzymatic Activity by Biomolecular Condensates through pH Buffering
Florence Stoffel, Marcell Papp, Marcos Gil-García, Andreas M. Küffner, Ana I. Benítez‐Mateos, Raphaël P. B. Jacquat, Nicola Galvanetto, Lenka Faltova, Paolo Arosio
This study shows that biomolecular condensates enhance enzymatic activity by buffering pH, allowing enzymes to function effectively in acidic conditions and enabling pH-dependent cascade reactions.
Nature Communications · Jul 10, 2025Peer-reviewedBiochemistry