Author

G. Besra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

A. Upton· 1 shared B. Urones· 1 shared C. A. Kulicke· 1 shared C. Gonzalez-Lopez· 1 shared D. Barros-Aguirre· 1 shared E. De Zan· 1 shared E. M. Perez-Herran· 1 shared E. N. Jimenez· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

A. Upton

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GSK2556286 is a novel antitubercular drug candidate effective in vivo with the potential to shorten tuberculosis treatment

E. Nuermberger, M. S. Martinez, O. Sanz, B. Urones, J. Esquivias, H. Soni, R. Tasneen, S. Tyagi, S.-Y. Li, P. J. Converse, H. I. Boshoff, G. T. Robertson, G. Besra, K. A. Abrahams, A. Upton, , E. N. Jimenez

Antimicrobial Agents and Chemotherapy · Jun 21, 2022Peer-reviewedPharmacology & Toxicology

The P5-ATPase ATP13A1 modulates MR1-mediated antigen presentation

C. A. Kulicke, E. De Zan, Z. Hein, C. Gonzalez-Lopez, S. Ghanwat, N. Veerapen, G. Besra, P. Klenerman, J. C. Christianson, S. Springer, S. Nijman, V. Cerundolo, M. Salio

This study identifies ATP13A1 as a key regulator of MR1 surface expression through CRISPR/Cas9 knockout experiments in human cell lines.

bioRxiv · May 26, 2021 · PreprintImmunology

Utilisation of the Prestwick Chemical Library (R) to identify drugs that inhibit the growth of Mycobacteria

L. J. Alderwick, P. Kanvatirth, G. Besra, R. E. Jeeves, J. Bacon

The paper screens FDA-approved drugs from the Prestwick Chemical Library against Mycobacterium species to identify antimycobacterial compounds and highlights potential drug repurposing targets.

bioRxiv · Jun 28, 2018Microbiology