Author

G. Blandino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Organism:human· 5 Research Focus:differential expression· 4 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

A. Sacconi· 3 shared C. Pulito· 2 shared E. Ruppin· 2 shared P. Muti· 2 shared R. Pellini· 2 shared S. Sinha· 2 shared S. Strano· 2 shared A. A. Ricci· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

A. Sacconi

Mutual co-authors in cluster

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5 papers

Recent·Most cited

Inactivation of p53 drives breast cancer brain metastasis by altering fatty acid metabolism

K. Laue, S. Pozzi, Y. Cohen-Sharir, T. Winkler, Y. Eliezer, S. Israeli Dangoor, A. Leikin-Frenkel, K. Lange, J. Zerbib, A. A. Ricci, A. Sacconi, J. Berthelet, A. Schaffer, W. Shi, Y. Liao, , U. Ben-David

This study shows that p53 inactivation promotes breast cancer brain metastasis by altering fatty acid metabolism, with implications for therapeutic targeting.

bioRxiv · Dec 20, 2023 · PreprintCancer Biology

Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissues

N. Sanghvi, C. Calvo-Alcaniz, P. Rajagopal, S. Scalera, V. Canu, S. Sinha, F. Schischlik, K. Wang, S. Madan, E. Shulman, A. Papanicolau-Sengos, G. Blandino, E. Ruppin, N. Nair

The paper compares gene expression in primary and metastatic tumors to their origin and target tissues, finding metastases more resemble target tissues and show reduced cancer hallmark activity.

bioRxiv · Oct 30, 2023Cancer Biology

Molecular profiling in HNSCC patients targets potential responsiveness to ICIs

A. Sacconi, P. Muti, C. Pulito, R. Pellini, S. Strano, P. Bossi, G. Blandino

The paper identifies immune gene signatures associated with response to immunotherapy in HNSCC patients, validated through TCGA and clinical cohorts.

bioRxiv · Dec 16, 2022 · PreprintCancer Biology

TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients.

A. Sacconi, S. Donzelli, C. Pulito, S. Ferrero, A. Morrone, M. Rigoni, F. Pimipinelli, F. Ensoli, G. Sanguineti, R. Pellini, N. Agrawal, E. Izumchenko, G. Ciliberto, A. Gianni, P. Muti, , G. Blandino

This study finds that TMPRSS2 expression is reduced in head and neck cancer tissues compared to normal tissues and is associated with poorer prognosis.

bioRxiv · Jun 16, 2020Cancer Biology

Division of labor between YAP and TAZ in non-small cell lung cancer

M. Shreberk-Shaked, B. Dassa, S. Sinha, S. Di Agostino, I. Azuri, Y. Aylon, G. Blandino, E. Ruppin, M. Oren

This study identifies distinct roles for YAP and TAZ in NSCLC, showing YAP regulates cell cycle and TAZ regulates extracellular matrix, with differential impacts on growth and migration.

bioRxiv · Jan 12, 2020Cancer Biology