Author

G. Hasenfuss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Wollnik· 2 shared A. Kraft· 1 shared A. M. Shah· 1 shared A. Maus· 1 shared A. Mirzaiebadizi· 1 shared A. Sasse· 1 shared A. V. Busley· 1 shared B. Meder· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

B. Wollnik

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome

A. V. Busley, O. Gutierrez-Gutierrez, E. Hammer, F. Koitka, A. Mirzaiebadizi, M. Steinegger, C. Pape, L. Boehmer, H. Schroeder, M. Kleinsorge, M. Engler, I. C. Cirstea, L. Gremer, D. Willbold, J. Altmueller, , L. Cyganek

This study identifies a novel LZTR1 variant causing cardiac hypertrophy by altering protein polymerization and ubiquitin ligase function, showing genetic correction can rescue the phenotype.

bioRxiv · Jan 10, 2023Cell Biology

Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients

L. Haupt, A. Maus, M. Tiburcy, S. Koehne, W. Maurer, R. Tappu, J. Haas, Y. Li, A. Sasse, C. Santos, R. Dressel, L. Wojnowski, G. Bunt, A. M. Shah, B. Meder, , K. Streckfuss-Bömeke

This study develops a human iPSC-CM model of DOX-induced cardiac dysfunction in B-cell lymphoma patients with high-dose DOX treatment, showing increased susceptibility to DOX toxicity and impaired mechanical function.

bioRxiv · Apr 15, 2020Cell Biology

Direct monitoring of cAMP at the cardiac ryanodine receptor using a novel targeted fluorescence biosensor mouse

F. Berisha, K. Goetz, J. Wegener, C. Jungen, U. Pape, A. Kraft, S. Warnke, D. Lindner, D. Westermann, S. Blankenberg, C. Meyer, G. Hasenfuss, S. Lehnart, V. Nikolaev

The paper develops a targeted fluorescence biosensor in transgenic mice to monitor cAMP levels near RyR2 in cardiomyocytes, revealing altered cAMP dynamics in cardiac hypertrophy.

bioRxiv · Apr 30, 2019 · PreprintCell Biology