Author

G. J. Hannon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 6

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Research Focus:clustering· 3 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Assay:imaging· 2 Assay:spatial transcriptomics· 2

Frequent Co-Authors

CRUK IMAXT Grand Challenge Team· 3 shared D. Bressan· 3 shared A. Dariush· 2 shared A. Nicholls· 2 shared B. Bodenmiller· 2 shared C. M. Mulvey· 2 shared F. Qosaj· 2 shared I. Cannell· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

CRUK IMAXT Grand Challenge Team

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Author profile →

6 papers

Recent·Most cited

The in vitro dynamics of pseudo-vascular network formation.

M.-E. Oraiopoulou, D.-L. Couturier, E. V. Bunce, I. Cannell, M. Golinska, G. J. Hannon, V. Sakkalis, S. E. Bohndiek

This study develops a framework to monitor and analyze the dynamic formation and dissolution of pseudo-vascular networks in vitro using time-resolved microscopy and image analysis, showing melanoma cells form the most stable networks and respond to specific drug treatments.

bioRxiv · Nov 2, 2023 · PreprintCancer Biology

Lineage plasticity in SCLC generates non-neuroendocrine cells primed for vasculogenic mimicry

S. M. Pearsall, S. C. Williamson, F. J. Garcia Marques, S. Humphrey, E. Hughes, Y. T. Shue, A. Bermudez, K. Frese, M. Galvin, M. Carter, L. Preist, A. Kerr, C. Zhou, T. G. Oliver, J. D. Humphries, , C. Dive

This study identifies VM-competent non-neuroendocrine cells in SCLC that support vessel formation and tumor growth through integrin β1-dependent ECM remodeling.

Journal of Thoracic Oncology · Oct 1, 2023Peer-reviewedCancer Biology

Creating a 'Timeline' of ductal carcinoma in situ to identify processes and biomarkers for progression towards invasive ductal carcinoma

C. A. Rebbeck, J. Xian, S. Bornelov, J. Geradts, A. Hobeika, H. Geiger, J. F. Alvarez, E. Rozhkova, A. Nicholls, N. Robine, H. K. Lyerly, G. J. Hannon

The paper generates a disease progression timeline for DCIS using gene expression data to identify early processes and biomarkers associated with progression to invasive breast cancer.

bioRxiv · Mar 1, 2022Cancer Biology

Clonal transcriptomics identifies mechanisms of chemoresistance and empowers rational design of combination therapies.

S. A. Wild, I. G. Cannell, K. Kania, A. Nicholls, D. Bressan, CRUK IMAXT Grand Challenge Team, G. J. Hannon, K. Sawicka

The paper uses clonal transcriptomics to identify mechanisms of chemoresistance in TNBC and suggests asparagine deprivation as a potential combination therapy.

bioRxiv · Dec 9, 2021Cancer Biology

Exploration and analysis of molecularly annotated, 3D models of breast cancer at single-cell resolution using virtual reality

D. Bressan, C. M. Mulvey, F. Qosaj, R. Becker, F. Grimaldi, S. Coffey, S. L. Vogl, L. Kuett, R. Catena, A. Dariush, C. Gonzalez Fernandez, E. A. Gonzalez Solares, M. Al Sa'd, A. Küpkü Yoldas, T. Whitmarsh, , G. J. Hannon

The paper introduces Theia, a virtual reality platform for exploring 3D molecularly annotated cancer datasets, and provides breast cancer datasets for analysis.

bioRxiv · Jun 28, 2021 · PreprintCancer Biology

The Imaging and Molecular Annotation of Xenografts and Tumours (IMAXT) High Throughput Data and Analysis Infrastructure

E. A. Gonzalez-Solares, A. Dariush, C. Gonzalez-Fernandez, A. Küpcü Yoldas, M. Al Sa'd, N. Millar, T. Whitmarsh, N. Chornay, I. Falciatori, A. Fatemi, D. Goodwin, L. Kuett, C. M. Mulvey, M. Paez Ribes, F. Qosaj, , N. A. Walton

The paper presents an infrastructure for high-throughput data and analysis of tumour and xenograft samples using multimodal imaging and molecular annotation.

bioRxiv · Jun 22, 2021Cancer Biology