Author

T. G. Oliver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. S. Ireland· 2 shared A. Bermudez· 1 shared A. Kerr· 1 shared A. R. Pandiri· 1 shared B. L. Witt· 1 shared B. M. Gruner· 1 shared C. A. Powell· 1 shared C. Dive· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

A. S. Ireland

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Author profile →

5 papers

Recent·Most cited

A Lung Cancer Mouse Model Database

L. Cai, Y. Gao, R. J. DeBerardinis, G. Acquaah-Mensah, V. Aidinis, J. E. Beane, S. Biswal, T. Chen, C. P. Concepcion-Crisol, B. M. Gruner, D. Jia, R. Jones, J. M. Kurie, M. G. Lee, P. Lindahl, , J. D. Minna

The paper establishes a database of lung cancer mouse models to improve data comparison and translational relevance by aligning mouse mutations with human lung cancer mutations.

bioRxiv · Feb 28, 2024 · PreprintCancer Biology

Lineage plasticity in SCLC generates non-neuroendocrine cells primed for vasculogenic mimicry

S. M. Pearsall, S. C. Williamson, F. J. Garcia Marques, S. Humphrey, E. Hughes, Y. T. Shue, A. Bermudez, K. Frese, M. Galvin, M. Carter, L. Preist, A. Kerr, C. Zhou, T. G. Oliver, J. D. Humphries, , C. Dive

This study identifies VM-competent non-neuroendocrine cells in SCLC that support vessel formation and tumor growth through integrin β1-dependent ECM remodeling.

Journal of Thoracic Oncology · Oct 1, 2023Peer-reviewedCancer Biology

KSR2 promotes self-renewal and clonogenicity of small-cell lung carcinoma

D. H. Huisman, D. Chatterjee, R. A. Svoboda, H. M. Vieira, A. S. Ireland, S. Skupa, J. W. Askew, D. E. Frodyma, L. Girard, K. W. Fisher, M. Kareta, J. Minna, T. G. Oliver, R. E. Lewis

This study shows KSR2 promotes self-renewal and clonogenicity in ASCL1-subtype SCLC by enhancing ERK signaling and tumor initiating capacity.

bioRxiv · Feb 11, 2022Cancer Biology

BET Inhibitors Target the SCLC-N subtype Small Cell Lung Cancer by Blocking NEUROD1 Transactivation

H. Chen, L. Gesumaria, Y.-K. Park, T. G. Oliver, D. S. Singer, K. Ge, D. S. Schrump

This study identifies BET bromodomain proteins as coactivators of NEUROD1 in SCLC, showing that BET inhibitors suppress NEUROD1-target genes and reduce tumor growth.

bioRxiv · Oct 25, 2021Cancer Biology

ASCL1 represses a latent osteogenic program in small cell lung cancer in multiple cells of origin

R. R. Olsen, D. W. Kastner, A. S. Ireland, S. M. Groves, K. Pozo, C. P. Whitney, M. R. Guthrie, S. J. Wait, D. Soltero, B. L. Witt, V. Quaranta, J. E. Johnson, T. G. Oliver

This study shows ASCL1 represses a latent osteogenic program in SCLC, promoting tumor initiation and preventing differentiation into bone tumors.

bioRxiv · Nov 11, 2020Cancer Biology