Author

S. S. Chung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. A. Lane· 1 shared A. Louissaint· 1 shared B. Kroger· 1 shared B. Posner· 1 shared C. Y. Park· 1 shared C. Zhang· 1 shared D. Hwang· 1 shared D. M. Weinstock· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. A. Lane

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Synergistic and antagonistic drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines

F. N. Kalkan, M. S. Yildiz, N. E. Wood, M. Farid, M. McCoy, C. Zhang, M. Lin, B. Posner, S. S. Chung, E. Toprak

This study investigates drug-drug interactions in AML cell lines, finding widespread but non-conserved synergistic and antagonistic effects across different cell lines.

bioRxiv · Feb 23, 2024Cancer Biology

CD99 Promotes Self-renewal in Hematopoietic Stem Cells and Leukemia Stem Cells by Regulating Protein Synthesis

Y. Huang, E. G. Kapti, Y. Ji, T. Thomas, J. Dempsey, K. Mims, I. Berezniuk, L. Guo, B. Kroger, W. Hu, C. Y. Park, S. S. Chung

This study shows CD99 regulates protein synthesis in hematopoietic stem cells and leukemia stem cells, promoting self-renewal and clonal expansion leading to AML.

bioRxiv · Feb 21, 2023Cancer Biology

SUMO-specific protease 2 (SENP2) suppresses browning of white adipose tissue through C/EBPβ modulation

J. S. Lee, S. Chae, J. Nan, Y. D. Koo, S.-A. Lee, Y. J. Park, D. Hwang, W. Han, Y.-B. Kim, S. S. Chung, K. S. Park

This study shows that SENP2 suppresses white adipose tissue browning by modulating C/EBPβ, leading to increased thermogenic gene expression and resistance to obesity in mice.

bioRxiv · Dec 16, 2020 · PreprintCell Biology

Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis

K. Togami, S. S. Chung, V. Madan, L. Cabal-Hierro, J. Taylor, S. S. Kim, G. K. Griffin, M. Ghandi, J. Li, Y. Y. Li, F. Angelot-Delettre, S. Biichle, M. Seiler, S. Buonamici, S. B. Lovitch, , A. A. Lane

The paper identifies sex-biased ZRSR2 mutations in BPDCN that impair pDC activation and apoptosis, linking X chromosome mutations to male-predominant leukemia.

bioRxiv · Oct 29, 2020Cancer Biology