Author

G. Lalazar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. F. Stenzel· 1 shared A. W. Ashbrook· 1 shared B. A. Ersoy· 1 shared B. Bosbach· 1 shared B. Razooky· 1 shared B. Zeck· 1 shared C. G. Fulmer· 1 shared C. M. Rice· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperPathology

A. F. Stenzel

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Author profile →

2 papers

Recent·Most cited

Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice

M. Kabbani, E. Michailidis, S. Steensels, C. G. Fulmer, J. M. Luna, J. Le Pen, M. Tardelli, B. Razooky, I. Ricardo-Lax, C. Zou, B. Zeck, A. F. Stenzel, C. Quirk, L. Foquet, A. W. Ashbrook, , Y. P. de Jong

This study shows that the PNPLA3 148M variant in human hepatocytes worsens non-alcoholic steatohepatitis in chimeric mice on a hypercaloric diet.

bioRxiv · Nov 19, 2020 · PreprintPathology

DNAJB1-PRKACA fusion kinase interacts with β-catenin and liver regenerative response to drive fibrolamellar hepatocellular carcinoma

E. R. Kastenhuber, G. Lalazar, D. F. Tschaharganeh, S. L. Houlihan, T. Baslan, C.-C. Chen, D. Requena, S. Tian, B. Bosbach, J. E. Wilkinson, S. M. Simon, S. W. Lowe

This study shows that the DNAJB1-PRKACA fusion kinase drives fibrolamellar hepatocellular carcinoma in mice and identifies β-catenin activation and environmental factors as contributors to tumor progression.

Proceedings of the National Academy of Sciences · Nov 21, 2017Peer-reviewedCancer Biology