Author

G. Ligresti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

N. Caporarello· 3 shared A. A. Raslan· 2 shared D. J. Tschumperlin· 2 shared D. L. Jones· 2 shared J. A. Meridew· 2 shared J. Lee· 2 shared K. M. Choi· 2 shared P. A. Link· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

N. Caporarello

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single Cell Transcriptomics of Fibrotic Lungs Unveils Aging-associated Alterations in Endothelial and Epithelial Cell Regeneration

A. A. Raslan, T. X. Pham, J. Lee, J. Hong, J. K. Schmottlach, K. Nicolas, M. D. Taha, A. M. Bujor, N. Caporarello, A. Thiriot, U. H. von Andrian, S. K. Huang, R. F. Nicosia, M. Trojanowska, X. Varelas, G. Ligresti

This study uses single-cell transcriptomics to analyze aging-related changes in lung regeneration and fibrosis in mice, identifying age-associated cellular and molecular alterations.

bioRxiv · Jan 17, 2023Pathology

Crystal ribcage: a platform for probing real-time lung function at cellular resolution in health and disease

R. Banerji, G. N. Grifno, L. Shi, D. Smolen, R. LeBourdais, J. Muhvich, C. Eberman, B. Hiller, J. Lee, K. Regan, S. Zheng, S. S. Zhang, J. Jiang, A. A. Raslan, J. C. Breda, , H. T. Nia

This paper introduces a transparent ribcage for real-time, cellular-resolution imaging of lung function in health and disease, revealing insights into tumor progression, immune responses, and disease remodeling.

bioRxiv · Oct 28, 2022 · PreprintBioengineering

Lung injury epigenetically primes mesenchyme for amplified activation upon re-injury

D. L. Jones, N. Caporarello, J. A. Meridew, K. M. Choi, A. J. Haak, P. A. Link, Q. Tan, T. Ordog, G. Ligresti, D. J. Tschumperlin

This study shows that lung mesenchyme retains epigenetic memory of prior injury, leading to amplified fibrogenic responses upon re-injury, with Runx1 playing a key role.

bioRxiv · Mar 4, 2022Cell Biology

ZNF416 is a pivotal transcriptional regulator of fibroblast mechano-activation

D. L. Jones, J. A. Meridew, M. T. Ducharme, K. L. Lydon, K. M. Choi, N. Caporarello, Q. Tan, P. A. Link, A. M. Diaz Espinosa, Y. Xiong, J.-H. Lee, Z. Ye, H. Yan, T. Ordog, G. Ligresti, , D. J. Tschumperlin

This study identifies ZNF416 as a key transcriptional regulator that mediates fibroblast responses to matrix stiffness through chromatin accessibility and gene expression changes.

bioRxiv · Jul 23, 2020Cell Biology