Author

Y. R. Miao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Giaccia· 2 shared A. C. Koong· 1 shared A. Diep· 1 shared A. N. Diep· 1 shared B. Wei· 1 shared C. Cenik· 1 shared C. Jia· 1 shared D. Jiang· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. J. Giaccia

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2 papers

Recent·Most cited

Developing High-Affinity Decoy Receptor Optimized for Multiple Myeloma and Diffuse Large B Cell Lymphoma Treatment

Y. R. Miao, K. Thakkar, C. Cenik, D. Jiang, K. Mizuno, C. Jia, G. C. Li, H. Zhao, A. Diep, J. Y. Xu, X. E. Zhang, T. T. C. Yang, M. Liedtke, P. Abidi, W.-s. Leung, , A. J. Giaccia

This paper develops an engineered sBCMA-Fc fusion protein with enhanced binding affinity to APRIL and BAFF, showing improved antitumor activity against multiple myeloma and diffuse large B cell lymphoma in preclinical models.

Journal of Experimental Medicine · Jul 26, 2022Peer-reviewedCancer Biology

Neutralizing PD-L1 and PD-L2 Enhances the Efficacy of Immune Checkpoint Inhibitors in Ovarian Cancer.

Y. R. Miao, K. N. Thakkar, J. Qian, M. S. Kariolis, W. Huang, S. A. Nandagopal, T. Yang, A. N. Diep, G. M. Cherf, Y. Xu, E. J. Moon, Y. Xiao, H. Alemany, T. Li, W. Yu, , A. J. Giaccia

The paper develops a high-affinity sPD-1 decoy molecule that neutralizes both PD-L1 and PD-L2, showing superior antitumor activity in ovarian cancer models compared to PD-1/PD-L1 antibodies.

bioRxiv · Jan 19, 2020 · PreprintCancer Biology