Author

G. M. Gillespie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. McMichael· 3 shared L. C. Walters· 2 shared B. D. Huisman· 1 shared B. F. Haynes· 1 shared C. Romagnani· 1 shared D. Li· 1 shared D. Rozbesky· 1 shared D. W. Cain· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

A. J. McMichael

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3 papers

Recent·Most cited

An unbiased characterization of the HLA-E and CD94/NKG2x peptide repertoire reveals peptide ligands that skew NK cell activation

B. D. Huisman, N. Guan, T. Ruckert, L. Garner, N. K. Singh, A. J. McMichael, G. M. Gillespie, C. Romagnani, M. E. Birnbaum

The paper identifies 500 HLA-E-bound peptides that bind CD94/NKG2A or CD94/NKG2C, revealing ligands that modulate NK cell activation.

bioRxiv · Aug 3, 2022Immunology

Mouse and Human Antibodies that Bind HLA-E-Leader Peptide Complexes and Enhance NK Cell Cytotoxicity

D. Li, S. Brackenridge, L. C. Walters, O. Swanson, K. Harlos, D. Rozbesky, D. W. Cain, K. Wiehe, R. M. Scearce, M. Barr, Z. Mu, R. Parks, M. Quastel, R. J. Edwards, Y. Wang, , B. F. Haynes

The paper isolates antibodies that bind HLA-E-Leader peptide complexes and enhance NK cell cytotoxicity in both mice and humans.

bioRxiv · Dec 3, 2020Immunology

Detailed and atypical HLA-E peptide binding motifs revealed by a novel peptide exchange binding assay

L. C. Walters, A. J. McMichael, G. M. Gillespie

The paper develops a novel peptide exchange ELISA assay to quantify HLA-E peptide binding and identifies both canonical and non-canonical peptides that bind HLA-E.

bioRxiv · May 5, 2020Immunology