Goal-directed action is transiently impaired in an hAPP-J20 mouse model of Alzheimer's disease, and in aging male mice regardless of genotype
A. Dhungana, S. Becchi, J. Leake, G. Morris, N. Avgan, B. Balleine, B. Vissel, L. A. Bradfield
The study shows that goal-directed action is temporarily impaired in Alzheimer's mouse models and aging males, linked to hippocampal neuroinflammation.
bioRxiv · Jul 25, 2022 · PreprintAnimal Behavior & Cognition