Author

G. Ofir

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:DNA methylation· 1

Frequent Co-Authors

R. Sorek· 3 shared A. Millman· 2 shared G. Amitai· 2 shared N. Tal· 2 shared S. Doron· 2 shared A. Bernheim· 1 shared A. Kacen· 1 shared A. Leavitt· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

R. Sorek

Mutual co-authors in cluster

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3 papers

Recent·Most cited

An expanding arsenal of immune systems that protect bacteria from phages

A. Millman, S. Melamed, A. Leavitt, S. Doron, A. Bernheim, J. Hör, A. Lopatina, G. Ofir, D. Hochhauser, A. Stokar-Avihail, N. Tal, S. Sharir, M. Voichek, Z. Erez, J. L. M. Ferrer, , R. Sorek

This study identifies 21 new bacterial defense systems against phages through genomic analysis and experiments, revealing novel protein domains and toxin-antitoxin mechanisms involved in anti-phage immunity.

bioRxiv · May 11, 2022Microbiology

Class I DISARM provides anti-phage and anti-conjugation activity by unmethylated DNA recognition

C. Aparicio-Maldonado, G. Ofir, A. Salini, R. Sorek, F. L. Nobrega, S. J. Brouns

This study identifies Class 1 DISARM as a system providing anti-phage and anti-conjugation activity through recognition of unmethylated DNA sites.

bioRxiv · Dec 28, 2021 · PreprintMicrobiology

Antiviral activity of bacterial TIR domains via signaling molecules that trigger cell death

G. Ofir, E. Herbst, M. Baroz, D. Cohen, A. Millman, S. Doron, N. Tal, D. B. A. Malheiro, S. Malitsky, G. Amitai, R. Sorek

This study identifies a bacterial antiviral pathway using TIR domains to produce a signaling molecule that triggers cell death via NAD depletion.

bioRxiv · Jan 6, 2021Microbiology