Author

G. P. Brittingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:mouse· 1 Organism:yeast· 1

Frequent Co-Authors

L. J. Holt· 2 shared M. Delarue· 2 shared A. Bazley· 1 shared B. D. Engel· 1 shared C. Jacobs-Wagner· 1 shared D. Fenyo· 1 shared F. Chang· 1 shared F. Ettefa· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

L. J. Holt

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Author profile →

2 papers

Recent·Most cited

nucGEMs probe the biophysical properties of the nucleoplasm

T. Shu, T. Szoradi, G. R. Kidiyoor, Y. Xie, N. L. Herzog, A. Bazley, M. Bonucci, S. Keegan, S. Saxena, F. Ettefa, G. P. Brittingham, J. Lemiere, D. Fenyo, F. Chang, M. Delarue, L. J. Holt

The paper introduces nucGEMs, fluorescent nanoparticles that probe nucleoplasm biophysical properties, revealing differences in motility, exclusion from heterochromatin, and effects of mitotic condensation.

bioRxiv · Nov 18, 2021 · PreprintBiophysics

mTORC1 controls phase-separation and the biophysical properties of the cytoplasm by tuning crowding

M. Delarue, G. P. Brittingham, S. Pfeffer, I. Surovtsev, K. J. Kennedy, S. Pinglay, J. I. Gutierrez, M. Schaffer, J. K. Chung, J. Plitzko, J. T. Groves, C. Jacobs-Wagner, B. D. Engel, L. J. Holt

The paper investigates how mTORC1 regulates macromolecular crowding and biophysical properties of the cytoplasm by using GEMs to measure diffusion and phase-separation changes.

bioRxiv · Dec 29, 2017Cell Biology