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2 papers
Recent·Most cited
Y. Guan, Z. Fang, A. Hu, S. Roberts, M. Wang, W. Ren, P. K. Johansson, S. C. Heilshorn, A. Enejder, G. Peltz
This study uses human hepatic organoids to identify pro-fibrotic signaling pathways and potential therapies for liver fibrosis.
bioRxiv · Apr 25, 2023 · PreprintCell Biology
Y. GUAN, A. Enejder, M. Wang, Z. Fang, L. Cui, S.-Y. Chen, J. Wang, Y. Tan, M. Wu, X. Chen, P. K. Johansson, I. Osman, K. Kunimoto, P. Russo, S. C. Heilshorn, G. Peltz
This study develops a human hepatic organoid model of ARPKD liver fibrosis, showing that the ARPKD mutation leads to fibrosis through TGFβ and PDGFRB pathways.
Nature Communications · Oct 22, 2021Peer-reviewedCell Biology