Author

G. T. Kozma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Szebeni· 3 shared T. Meszaros· 3 shared T. Radovits· 3 shared B. A. Barta· 2 shared B. Merkely· 2 shared P. Berenyi· 2 shared R. Facsko· 2 shared T. Bakos· 2 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersImmunology

J. Szebeni

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Author profile →

3 papers

Recent·Most cited

mRNA-LNP COVID-19 vaccine lipids induce low level complement activation and production of proinflammatory cytokines: Mechanisms, effects of complement inhibitors, and relevance to adverse reactions

T. Bakos, T. Meszaros, G. T. Kozma, P. Berenyi, R. Facsko, H. Farkas, L. Dezsi, C. Heirman, S. de Koker, R. Schiffelers, K. A. Glatter, T. Radovits, G. Szenasi, J. Szebeni

This study investigates how mRNA-LNP vaccines trigger complement activation and cytokine production, linking these processes to inflammatory adverse events and suggesting potential therapeutic strategies.

bioRxiv · Jan 12, 2024Immunology

The COVID-19 mRNA vaccine Comirnaty induces anaphylactic shock in an anti-PEG hyperimmune large animal model: Role of complement in cardiovascular, hematological, and inflammatory mediator changes

B. A. Barta, T. Radovits, A. B. Dobos, G. T. Kozma, T. Meszaros, P. Berenyi, R. Facsko, T. G. Fulop, B. Merkely, J. Szebeni

This study shows that anti-PEG antibodies cause anaphylactic shock in pigs after Comirnaty vaccination, with complement activation and TXA2 release contributing to the reaction.

bioRxiv · May 19, 2023 · PreprintPharmacology & Toxicology

Zymosan-induced leukocyte and cytokine changes in pigs: a new model for streamlined drug testing against severe COVID-19

G. Kokeny, T. Bakos, B. A. Barta, G. V. Nagy, T. Meszaros, G. T. Kozma, A. Szabo, J. Szebeni, B. Merkely, T. Radovits

This paper develops a pig model of zymosan-induced immune and hemodynamic changes that mimic late-stage COVID-19 symptoms, enabling drug testing for cytokine storm.

bioRxiv · Sep 23, 2022 · PreprintImmunology