Author

T. Radovits

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:plant (other)· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Merkely· 3 shared G. T. Kozma· 3 shared J. Szebeni· 3 shared T. Meszaros· 3 shared B. A. Barta· 2 shared P. Berenyi· 2 shared R. Facsko· 2 shared T. Bakos· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPharmacology & Toxicology

B. Merkely

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

mRNA-LNP COVID-19 vaccine lipids induce low level complement activation and production of proinflammatory cytokines: Mechanisms, effects of complement inhibitors, and relevance to adverse reactions

T. Bakos, T. Meszaros, G. T. Kozma, P. Berenyi, R. Facsko, H. Farkas, L. Dezsi, C. Heirman, S. de Koker, R. Schiffelers, K. A. Glatter, T. Radovits, G. Szenasi, J. Szebeni

This study investigates how mRNA-LNP vaccines trigger complement activation and cytokine production, linking these processes to inflammatory adverse events and suggesting potential therapeutic strategies.

bioRxiv · Jan 12, 2024Immunology

The COVID-19 mRNA vaccine Comirnaty induces anaphylactic shock in an anti-PEG hyperimmune large animal model: Role of complement in cardiovascular, hematological, and inflammatory mediator changes

B. A. Barta, T. Radovits, A. B. Dobos, G. T. Kozma, T. Meszaros, P. Berenyi, R. Facsko, T. G. Fulop, B. Merkely, J. Szebeni

This study shows that anti-PEG antibodies cause anaphylactic shock in pigs after Comirnaty vaccination, with complement activation and TXA2 release contributing to the reaction.

bioRxiv · May 19, 2023 · PreprintPharmacology & Toxicology

Truncated titin is integrated into the human dilated cardiomyopathic sarcomere

D. Kellermayer, H. Tordai, B. Kiss, G. Török, D. M. Peter, A. A. Sayour, M. Polos, I. Hartyanszky, B. Szilveszter, S. Labeit, A. Gango, G. Bedics, C. Bödör, T. Radovits, B. Merkely, M. Kellermayer

The paper investigates TTNtv mutations in DCM by analyzing cardiac samples, finding truncated titin integrated into sarcomeres with structural defects.

bioRxiv · Feb 8, 2023 · PreprintBiophysics

Zymosan-induced leukocyte and cytokine changes in pigs: a new model for streamlined drug testing against severe COVID-19

G. Kokeny, T. Bakos, B. A. Barta, G. V. Nagy, T. Meszaros, G. T. Kozma, A. Szabo, J. Szebeni, B. Merkely, T. Radovits

This paper develops a pig model of zymosan-induced immune and hemodynamic changes that mimic late-stage COVID-19 symptoms, enabling drug testing for cytokine storm.

bioRxiv · Sep 23, 2022 · PreprintImmunology