Author

G. Vadlamani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:protein structure· 3 Organism:plant (other)· 2 Research Focus:protein structure prediction· 2 Organism:Arabidopsis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

J. S. Mylne· 4 shared M. F. Fisher· 4 shared C. D. Payne· 3 shared K. J. Rosengren· 3 shared R. J. Clark· 3 shared C. S. Bond· 2 shared F. Hajiaghaalipour· 2 shared J. Zhang· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersBiochemistry

J. S. Mylne

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Author profile →

4 papers

Recent·Most cited

Crystal structure of Arabidopsis thaliana HPPK/DHPS, a bifunctional enzyme and target of the herbicide asulam

G. Vadlamani, K. V. Sukhoverkov, J. Haywood, K. J. Breese, M. F. Fisher, K. A. Stubbs, C. S. Bond, J. S. Mylne

The paper solves the crystal structure of Arabidopsis thaliana HPPK/DHPS, revealing structural conservation with bacterial enzymes and exploring the herbicidal and antibacterial activity of asulam and related compounds.

bioRxiv · Nov 10, 2021Biochemistry

Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides

C. D. Payne, G. Vadlamani, F. Hajiaghaalipour, T. Muhammad, M. F. Fisher, H. S. Andersson, U. Göransson, R. J. Clark, C. S. Bond, J. S. Mylne, K. J. Rosengren

The paper uses solution NMR and racemic crystallography to characterize the structure of PDP-23 and related peptides, revealing their unique folding and potential as drug scaffolds.

bioRxiv · Jul 28, 2021Biochemistry

A Chameleonic Macrocyclic Peptide with Drug Delivery Applications

C. D. Payne, B. Franke, M. F. Fisher, F. Hajiaghaalipour, C. E. McAleese, A. Song, C. Eliasson, J. Zhang, A. Jayasena, G. Vadlamani, R. J. Clark, R. F. Minchin, J. S. Mylne, K. J. Rosengren

The paper describes a chameleonic macrocyclic peptide, PDP-23, which can adopt different structures and is used to create a cell-penetrating inhibitor of the P-glycoprotein drug efflux pump.

bioRxiv · Dec 16, 2020 · PreprintBiochemistry

Defining the familial fold of the vicilin-buried peptide family

C. D. Payne, G. Vadlamani, M. F. Fisher, J. Zhang, R. J. Clark, J. S. Mylne, K. J. Rosengren

The paper characterizes the structural features of Vicilin Buried Peptides (VBPs) using solution NMR spectroscopy, revealing a helix-loop-helix hairpin fold stabilized by disulfide bonds and inter-helix interactions.

bioRxiv · May 26, 2020Biochemistry