Author

G.-B. Tian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:whole-genome sequencing· 3 Organism:E. coli· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:genome assembly· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

L.-L. Zhong· 4 shared S. Feng· 3 shared D. L. Paterson· 2 shared G. Chen· 2 shared H. Zhao· 2 shared J. Li· 2 shared L. Liang· 2 shared L. Zhang· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersMicrobiology

L.-L. Zhong

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of a novel MCR-1 variant displaying low level of co-resistance to β-lactam antibiotics that uncovers a potential novel antimicrobial peptide

L. Liang, L.-L. Zhong, L. Wang, D. Zhou, Y. Li, J. Li, Y. Chen, W. Liang, W. Wei, C. Zhang, H. Zhao, L. Lyu, N. Stoesser, Y. Doi, D. L. Paterson, , G.-B. Tian

The paper identifies a novel MCR-1 variant with low β-lactam co-resistance and shows synthetic peptides from this variant have broad-spectrum antimicrobial activity.

bioRxiv · Apr 3, 2023 · PreprintMicrobiology

The fitness landscape of the mobilized colistin resistance gene mcr-1

Z. Guo, S. Feng, L. Liang, J. Li, L.-L. Zhong, H. Zhao, G.-b. Tian, J.-R. Yang

The paper generates and analyzes an mcr-1 mutant library to assess the impact of mutations on colistin resistance, finding that most mutations in the catalytic domain reduce resistance.

bioRxiv · Jul 21, 2022 · PreprintEvolutionary Biology

Emergence of a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Co-harbouring a blaNDM-1-carrying Virulent Plasmid and a blaKPC-2-carrying Plasmid in an Egyptian Hospital

M. A. E.-G. El-Sayed Ahmed, Y. Yang, Y. Yang, B. Yan, G. Chen, R. M. Hassan, L.-l. Zhong, Y. Chen, A. P. Roberts, Y. Wu, R. He, X. Liang, M. Qin, M. Dai, L. Zhang, , G.-B. Tian

This study identifies a hypervirulent CRKP strain in Egypt carrying two plasmids with carbapenemase and virulence genes, highlighting the genetic basis of resistance and virulence.

bioRxiv · Feb 26, 2021Microbiology

Dynamics of mcr-1 prevalence and mcr-1-positive Escherichia coli after the cessation of colistin use as a feed additive for animals in China: a prospective cross-sectional and whole genome sequencing based molecular epidemiological study

C. Shen, L.-L. Zhong, Y. Yang, Y. Doi, D. L. Paterson, N. Stoesser, F. Ma, M. A. E.-G. E.-S. Ahmed, S. Feng, S. Huang, H.-Y. Li, X. Huang, X. Wen, Z. Zhao, M. Lin, , G.-B. Tian

This study tracks the decline of mcr-1 prevalence and genetic changes in mcr-1-positive Escherichia coli after China banned colistin use in animal feed.

bioRxiv · Feb 3, 2020Microbiology