Author

G.-C. Yuan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Bourreille· 1 shared A. D. Polydorides· 1 shared A. Fantou· 1 shared A. Krek· 1 shared A. L. Greenleaf· 1 shared A. Livanos· 1 shared A. Nguyen· 1 shared A. V. Grassetti· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Bourreille

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Author profile →

2 papers

Recent·Most cited

Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis.

D. Jha, Z. Al-Taie, A. Krek, S. T. Eshghi, A. Fantou, T. Laurent, M. Tankelevich, X. Cao, H. Meringer, A. Livanos, M. Tokuyama, F. Cossarini, A. Bourreille, R. Josien, R. Hou, , S. Mehandru

The paper identifies myeloid cell influx and epithelial cell perturbations in ulcerative colitis, linking them to disease severity and anti-TNF therapy non-response.

bioRxiv · Jun 2, 2023 · PreprintImmunology

CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation

M. Krajewska, R. Dries, A. V. Grassetti, S. Dust, Y. Gao, H. Huang, B. Sharma, D. S. Day, N. Kwiatkowski, M. Pomaville, O. Dodd, E. Chipumuro, T. Zhang, A. L. Greenleaf, G.-C. Yuan, , R. E. George

This study shows CDK12 inhibition causes premature cleavage and polyadenylation in long DNA damage response genes, linked to their length and polyadenylation site distribution.

bioRxiv · Nov 30, 2018Cancer Biology