Author

R. Josien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:benchmark study· 1

Frequent Co-Authors

C. Braudeau· 4 shared J. C. Martin· 3 shared T. Laurent· 3 shared A. Bourreille· 2 shared A. Fantou· 2 shared A. Moreau· 2 shared C. Fourgeux· 2 shared F. Coulon· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersImmunology

C. Braudeau

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis.

D. Jha, Z. Al-Taie, A. Krek, S. T. Eshghi, A. Fantou, T. Laurent, M. Tankelevich, X. Cao, H. Meringer, A. Livanos, M. Tokuyama, F. Cossarini, A. Bourreille, R. Josien, R. Hou, , S. Mehandru

The paper identifies myeloid cell influx and epithelial cell perturbations in ulcerative colitis, linking them to disease severity and anti-TNF therapy non-response.

bioRxiv · Jun 2, 2023 · PreprintImmunology

A gene-expression module in circulating immune cells is associated with cell migration during immune diseases.

D. Sinha, T. Laurent, A. Broquet, C. Fourgeux, T. Letellier, G. Tilly, S. Bruneau, S. Ville, L. Bouchet-Delbos, J. Branchereau, C. Kerleau, S. Brouard, G. Blancho, M. Giral, R. Josien, , J. Poschmann

The paper identifies a gene expression module in circulating immune cells linked to migration during immune diseases and shows its role in tissue recruitment and immune activation.

bioRxiv · Apr 11, 2023Immunology

IL-22BP production is heterogeneously distributed in Crohn's disease

A. Fantou, E. Lagrue, T. Laurent, L. Delbos, S. Blandin, A. Jarry, G. Beriou, C. Braudeau, N. Salabert-Le Guen, E. Marin, A. Moreau, J. Podevin, A. Bourreille, R. Josien, J. C. Martin

This study investigates IL-22BP production and distribution in Crohn's disease tissues, finding higher levels in ileum and associations with eosinophils, moDCs, and smoking.

bioRxiv · Apr 7, 2021Immunology

Non-permissive human conventional CD1c+ dendritic cells enable trans-infection of human primary renal tubular epithelial cells and protect BK polyomavirus from neutralization

M. Sikorski, F. Coulon, C. Peltier, C. Braudeau, A. Garcia, M. Giraud, K. Autain-Renaudin, C. Kandel-Aznar, S. Nedellec, P. Hulin, J. Branchereau, J. Veziers, P. Gaboriaud, A. Touze, J. Burlaud-Gaillard, , F. Halary

This study shows that CD1c+ dendritic cells can transmit BKPyV to epithelial cells and protect the virus from neutralization.

bioRxiv · Sep 4, 2020Microbiology

An easy and reliable whole blood freezing method for flow cytometry immuno- phenotyping and functional analyses

C. Braudeau, N. Salabert-Le Guen, J. Chevreuil, M. Rimbert, J. C. Martin, R. Josien

This paper introduces a whole blood freezing method using CryoStor(R) CS10 solution, demonstrating preserved cell viability and functional markers for flow cytometry analyses.

bioRxiv · Aug 12, 2020Immunology

Dendritic cells require TMEM176A/B ion channels for optimal MHC II antigen presentation to naive CD4+ T cells

M. Lancien, G. Bienvenu, L. Gueno, S. Salle, E. Merieau, S. Remy, A. Even, A. Moreau, A. Molle, C. Fourgeux, F. Coulon, G. Beriou, L. Bouchet-Delbos, E. Chiffoleau, P. Kirstetter, , C. Louvet

The paper shows TMEM176A/B ion channels are essential for dendritic cells to present antigens to CD4+ T cells, but not for Th17 or ILC3 function.

bioRxiv · May 1, 2020 · PreprintImmunology

Immunological characterization of a rat model of Duchenne’s disease and demonstration of improved muscle strength after anti-CD45RC antibody treatment

L.-H. Ouisse, S. Remy, A. Lafoux, T. Larcher, L. Tesson, V. Chenouard, C. Guillonneau, L. Brusselle, N. Vimond, K. Rouger, Y. Pereon, A. Chenouard, C. Gras-Le Guen, C. Braudeau, R. Josien, , I. Anegon

This study characterizes immune responses in a rat model of Duchenne’s disease and shows that anti-CD45RC antibody treatment improves muscle strength without side effects.

bioRxiv · Sep 3, 2018Immunology