Author

G.-M. Lu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 2 Research Focus:protein structure prediction· 2 Organism:Drosophila· 1 Organism:E. coli· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. Yin· 3 shared C.-C. Chang· 3 shared C.-J. Guo· 3 shared J. Zhong· 3 shared J.-L. Liu· 3 shared T. Zhang· 3 shared X. Zhou· 3 shared H.-H. Hu· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersBiochemistry

B. Yin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis of human PRPS2 filaments

G.-M. Lu, H.-H. Hu, C.-C. Chang, J. Zhong, X. Zhou, C.-J. Guo, T. Zhang, Y.-L. Li, B. Yin, J.-L. Liu

This study determines the structure of hPRPS2 polymers using cryo-EM, revealing how ADP binding affects polymerization and catalytic activity.

bioRxiv · Jul 11, 2022 · PreprintBiochemistry

Allosteric inhibition of PRPS is moderated by filamentous polymerization

H. Hu, G.-M. Lu, C.-C. Chang, Y. Li, J. Zhong, C.-J. Guo, X. Zhou, B. Yin, T. Zhang, J.-L. Liu

The paper investigates two filament structures of E. coli PRPS resolved by Cryo-EM, revealing how ligand binding modulates allosteric inhibition and PRPP production.

bioRxiv · Apr 28, 2022Biochemistry

Structural basis of dynamic P5CS filaments

J. Zhong, C.-J. Guo, X. Zhou, C.-C. Chang, B. Yin, T. Zhang, H.-H. Hu, G.-M. Lu, J.-L. Liu

This study determines the structure of Drosophila P5CS filament, revealing how filamentation coordinates GK and GPR domains for catalysis.

bioRxiv · Dec 2, 2021Biochemistry