B. Yin

Molecular Basis for RNA Cytidine Acetylation by NAT10

This study determines the cryo-EM structure of NAT10 bound to a cytidine-CoA probe, revealing its mechanism for RNA N4-cytidine acetylation and its role in cellular processes.

The kinematics and aerodynamics of hinged wing of honeybees during takeoff

This study analyzes honeybee wing kinematics during takeoff, revealing key parameters and the role of hinged wings in thrust generation.

Cell Type Specific Responses of the Endoplasmic Reticulum Dynamics to Environmental Stress

This study develops a super-resolution imaging and analysis method to study ER dynamics in Arabidopsis under environmental stress, revealing correlations between ER structure parameters and growth features.

Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP

This study demonstrates that lipid nanoparticle-delivered thermostable Cas9 RNPs achieve high-efficiency genome editing in mouse liver and lung tissues.

Inducible nitric oxide synthase (iNOS) is necessary for GBP-mediated T. gondii restriction in murine macrophages via vacuole nitration and intravacuolar network collapse

22kHz Ultrasonic Vocalizations and Body Freezing May Represent Two Systems of Fear in Rodent Fear Conditioning Paradigms

This study investigates two fear responses in rodents, finding that 22kHz ultrasonic vocalizations reflect subjective fear while body freezing indicates an automatic defensive response.

Host and transmission route of Enterocytozoon hepatopenaei (EHP) from dragonfly to shrimp

This study identifies dragonflies as natural hosts of EHP and confirms horizontal transmission between dragonflies and shrimp.

An Empirical Study on the Motivation of Helping Behavior in Rats

This study investigates the motivations for helping behavior in rats through three experiments, finding that social contact and environmental interest are primary motivators, while distress alleviation and prior social experience influence behavior onset and persistence.

Lipid Driven Inter-leaflet Coupling of Plasma Membrane Order Regulates FcεRI Signaling in Mast Cells

This study shows that lipid-driven interleaflet coupling in mast cell membranes regulates FcεRI signaling by modulating inner leaflet order through outer leaflet lipid exchange.

Structural basis of human PRPS2 filaments

This study determines the structure of hPRPS2 polymers using cryo-EM, revealing how ADP binding affects polymerization and catalytic activity.

The complex roles of genomic DNA modifications of bacteriophage T4 in resistance to nuclease-based defense systems of E. coli

The paper investigates how genomic modifications in phage T4 DNA affect its resistance to nuclease-based defense systems in E. coli, revealing roles beyond simple DNA degradation prevention.

Allosteric inhibition of PRPS is moderated by filamentous polymerization

The paper investigates two filament structures of E. coli PRPS resolved by Cryo-EM, revealing how ligand binding modulates allosteric inhibition and PRPP production.

Structural basis of dynamic P5CS filaments

This study determines the structure of Drosophila P5CS filament, revealing how filamentation coordinates GK and GPR domains for catalysis.

Automated Spatially Targeted Optical Micro Proteomics (AutoSTOMP) 2.0 identifies proteins enriched within inflammatory lesions in tissue sections and human clinical biopsies.

AutoSTOMP 2.0 identifies proteins in specific regions of tissue sections and biopsies, revealing inflammatory proteins in cardiac infarcts and IgG4+ lesions.

Association of gut microbiota with cerebral cortex and cerebrovascular abnormality in human mild traumatic brain injury

This study identifies gut microbiota changes and their associations with cerebral cortex and cerebrovascular abnormalities in human mild traumatic brain injury.

Comparison of three glycoproteomic methods for the analysis of CHO cells treated with 1,3,4-O-Bu3ManNAc

The paper compares three glycoproteomic methods for analyzing N-linked glycosites in CHO cells treated with 1,3,4-O-Bu3ManNAc, finding that NGAG identifies more glycosites than SPEG and HILIC.

Automated Spatially Targeted Optical Micro Proteomics (autoSTOMP) to determine protein complexity of subcellular structures

The paper introduces autoSTOMP, an automated protocol for spatially targeted optical micro proteomics, enabling efficient protein analysis of subcellular structures in human and mouse cells.

βVPE is involved in tapetal degradation and pollen development by activating proprotease maturation in Arabidopsis thaliana

This study identifies βVPE as a key enzyme in Arabidopsis thaliana that activates proproteases for tapetal degradation and pollen development.

Penaeidins are a novel family of antiviral effectors against WSSV in shrimp

This study identifies penaeidins as antiviral effectors in shrimp that bind WSSV virions, inhibit viral entry, and are regulated by Toll and IMD pathways.

RNAi screening identifies a new Toll from shrimp that restricts WSSV infection through activating Dorsal to induce antimicrobial peptides