Orchestration of alternative splicing regulates bone marrow mesenchymal stem cells fate during aging
Y. Xiao, G.-P. Cai, X. Feng, Q. Guo, Y. Huang, T. Su, C.-J. Li, X.-H. Luo, Y.-J. Zheng, M. Yang
This study identifies YBX1 deficiency causes mis-splicing in BMSCs, leading to senescence and bone loss, and shows Sciadopitysin can reverse this process.
bioRxiv · May 27, 2022 · PreprintCell Biology