Author

Yuxin Zhu

University of PennsylvaniaORCID 0000-0002-8932-628XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:rat· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:non-human primate· 1 Research Focus:protein design· 1

Frequent Co-Authors

Dennis R. BurtoniD· 4 shared Gabriel AvillioniD· 4 shared Nitesh MishraiD· 4 shared Raiees AndrabiiD· 4 shared Rebecca NedelleciD· 4 shared Rohan Roy ChowdhuryiD· 4 shared Sean CallaghaniD· 4 shared Xuduo LiiD· 4 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Dennis R. BurtonORCID

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4 papers

Recent·Most cited

Early clonal dominance at priming sets the trajectory for broad HIV serum neutralization

Bo Liang, Yuxin Zhu, Ryan S. Roark, Xuduo Li, Nitesh Mishra, Christian L. Martella, Anh L. Vo, Gabriella Giese, Qin Huang, Andrea Biju, Lifei Tjio, Rohan Roy Chowdhury, Prabhgun Oberoi, Khaled Amereh, Areeba A. Wani, , Raiees Andrabi

The paper shows that early clonal dominance in B-cell precursors after vaccination predicts the breadth of HIV-neutralizing antibodies in rhesus macaques.

bioRxiv · Oct 27, 2026 · PreprintImmunology

Protective pan-betacoronavirus neutralizing antibodies by vaccination

Pan-Pan Zhou, Ziqi Feng, Wan-ting He, Yuxin Zhu, Meng Yuan, Xuduo Li, Yuexiu Zhang, Lina Vo, Tazio Capozzola, Sean Callaghan, Nitesh Mishra, Gabriel Avillion, Katharina Dueker, Bo Liang, Rohan Roy Chowdhury, , Raiees Andrabi

Epitope-focused S2 stem-helix nanoparticle immunogens elicit protective broadly neutralizing antibodies against diverse betacoronaviruses in non-human primates, establishing a framework for pan-betacoronavirus vaccines.

bioRxiv · Aug 7, 2026 · PreprintImmunology

Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques

Nitesh Mishra, Bo Liang, Ryan S. Roark, Amrit Raj Ghosh, Sean Callaghan, Wen-Hsin Lee, Xuduo Li, Anh L. Vo, Gabriel Avillion, Rohan Roy Chowdhury, Rumi Habib, Frédéric Bibollet‐Ruche, Gabriella Giese, Prabhgun Oberoi, Khaled Amereh, , Raiees Andrabi

This study shows that a germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques by priming V2-apex bnAb B cell precursors.

Immunity · Apr 1, 2026Peer-reviewedImmunology

Structure-guided design of native-like HIV Env Single Chain Trimers for enhanced stability, immunogenicity, and versatile vaccine delivery

Xuduo Li, Ipsita Krishnamurthy, Nitesh Mishra, Nicole E. James, Rohan Roy Chowdhury, Sean Callaghan, Anjali Somanathan, Gabriel Avillion, Khaled Amereh, Tharunika Sekar, Prabhgun Oberoi, Yuxin Zhu, Jonathan L. Torres, Wen-Hsin Lee, Joel D. Allen, , Raiees Andrabi

The paper designs native-like HIV Env single-chain trimers (SCTs) that are stable, immunogenic, and compatible with vaccine delivery methods.

bioRxiv · Oct 25, 2025 · PreprintImmunology