Native-like soluble E1E2 glycoprotein heterodimers on self-assembling protein nanoparticles for hepatitis C virus vaccine design
Linling He, Yi-Zong Lee, Yi-Nan Zhang, Maddy L. Newby, Benjamin M. Janus, Fabrizio G. Gonzalez, Garrett Ward, Connor DesRoberts, Shr-Hau Hung, Erick Giang, Joel D. Allen, Liudmila Kulakova, Eric A. Toth, Thomas R. Fuerst, Mansun Law, , Jiang Zhu
The paper designs, characterizes, and tests a soluble HCV E1E2 heterodimer and self-assembling nanoparticles for vaccine development.
Nature Communications · Feb 11, 2026Peer-reviewedMicrobiology