Author

Gerald Hysenaj

Newcastle University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

David J. ElliottiD· 4 shared Caroline DalglieshiD· 3 shared Ingrid E. Ehrmann· 3 shared Jennifer MunkleyiD· 3 shared Kathleen CheungiD· 3 shared Simon CockelliD· 3 shared Chileleko Siachisumo· 2 shared Graham R. SmithiD· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMolecular Biology

David J. ElliottORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression

Chileleko Siachisumo, Sara Luzzi, Saad Aldalaqan, Gerald Hysenaj, Caroline Dalgliesh, Kathleen Cheung, Matthew R. Gazzara, Ivaylo D Yonchev, Katherine James, Mahsa Kheirollahi Chadegani, Ingrid E. Ehrmann, Graham R. Smith, Simon Cockell, Jennifer Munkley, Stuart A. Wilson, , David J. Elliott

This study shows RBMX and RBMXL2 proteins regulate splicing of ultra-long exons by repressing cryptic splice sites, with RBMXL2 rescuing splicing defects in somatic cells.

eLife · Sep 9, 2024Peer-reviewedMolecular Biology

RBMX enables productive RNA processing of ultra-long exons important for genome stability

Sara Luzzi, Gerald Hysenaj, Chileleko Siachisumo, Kathleen Cheung, Matthew R. Gazzara, Katherine James, Caroline Dalgliesh, Mahsa Kheirollahi Chadegani, Ingrid E. Ehrmann, Graham R. Smith, Simon Cockell, Jennifer Munkley, Yoseph Barash, David J. Elliott

The paper shows RBMX prevents non-productive splicing of ultra-long exons, maintaining genome stability by blocking aberrant splice sites in genes like ETAA1.

bioRxiv · Oct 9, 2020 · PreprintMolecular Biology

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

Jennifer Munkley, Ling Li, S R Gokul Krishnan, Gerald Hysenaj, Emma Scott, Caroline Dalgliesh, Htoo Zarni Oo, Teresa Mendes Maia, Kathleen Cheung, Ingrid E. Ehrmann, Karen E. Livermore, Hanna Zielinska, Oliver Thompson, Bridget Knight, Paul J. McCullagh, , David J. Elliott

The paper shows androgen-regulated ESRP2 transcription controls alternative splicing in prostate cancer, with implications for metastasis.

eLife · Sep 3, 2019Peer-reviewedMolecular Biology

SUPPA2 provides fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions

Juan L. Trincado, Juan Carlos Entizne, Gerald Hysenaj, Babita Singh, Miha Škalič, David J. Elliott, Eduardo Eyras

Genome biology · Mar 23, 2018Peer-reviewedBioinformatics