Author

Giselle Barbosa-Lima

Instituto Nacional de Infectologia Evandro Chagas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:metagenomics· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Fernando A. BozzaiD· 4 shared Thiago Moreno L. SouzaiD· 3 shared Yasmine Rangel VieiraiD· 3 shared Aaron E. LiniD· 2 shared Adrianne D. GladdeniD· 2 shared Amanda L. TaniD· 2 shared Andreas GnirkeiD· 2 shared Christian B. Matranga· 2 shared

Activity by Year

2016-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersGenomics

Fernando A. BozzaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Emergence of the East-Central-South-African genotype of Chikungunya virus in Brazil and the city of Rio de Janeiro may have occurred years before surveillance detection

Thiago Moreno L. Souza, Yasmine Rangel Vieira, Edson Oliveira Delatorre, Giselle Barbosa-Lima, Raul Leal Faria Luiz, Alexandre Gomes Vizzoni, Komal Jain, Milene Dias Miranda, Nishit Bhuva, Jan F. Gogarten, James Ng, Riddhi Thakkar, Andrea Surrage Calheiros, Ana Paula Teixeira Monteiro, Patrícia Torres Bozza, , Nischay Mishra

Scientific Reports · Feb 26, 2019Peer-reviewedGenomics

Capturing diverse microbial sequence with comprehensive and scalable probe design

Hayden C. Metsky, Katherine J. Siddle, Adrianne D. Gladden, James Qu, David K. Yang, Patrick Brehio, Andrew Goldfarb, Anne L Piantadosi, Shirlee Wohl, Amber Carter, Aaron E. Lin, Kayla G. Barnes, Damien C. Tully, Björn Corleis, Scott Hennigan, , Christian B. Matranga

The paper introduces CATCH, a method for designing compact and scalable probe sets to enhance metagenomic sequencing sensitivity, demonstrating improved viral genome recovery and diversity preservation.

Nature Biotechnology · Feb 1, 2019Peer-reviewedGenomics

Genome sequencing reveals Zika virus diversity and spread in the Americas

Hayden C. Metsky, Christian B. Matranga, Shirlee Wohl, Stephen F. Schaffner, Catherine A. Freije, Sarah M. Winnicki, Kendra L. West, James Qu, Mary Lynn Baniecki, Adrianne D. Gladden, Aaron E. Lin, Christopher H. Tomkins-Tinch, Simon H. Ye, Daniel J. Park, Cynthia Y. Luo, , Pardis Christine Sabeti

This study sequenced 110 Zika virus genomes from 10 countries, revealing rapid expansion in Brazil, multiple introductions into other regions, and undetected circulation before confirmed cases.

Nature · May 23, 2017Peer-reviewedGenomics

The clinically approved antiviral drug sofosbuvir impairs Brazilian zika virus replication

Caroline Q. Sacramento, Gabrielle R. de Melo, Natasha Rocha, Lucas Villas Boas Hoelz, Milene Mesquita, Caroline S. de Freitas, Natalia Fintelman-Rodrigues, Andressa Marttorelli, Andre C. Ferreira, Giselle Barbosa-Lima, Monica M. Bastos, Eduardo de Mello Volotao, Diogo A. Tschoeke, Luciana Leomil, Fernando A. Bozza, , Thiago Souza

This study shows sofosbuvir inhibits Brazilian ZIKV replication by targeting RNA polymerase, suggesting it as a potential antiviral for ZIKV.

bioRxiv · Jul 6, 2016Microbiology