Author

Graeme Smith

Artios Pharma Limited (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Aaron M. WengeriD· 1 shared Andrew W. CarrolliD· 1 shared Azza E. AhmediD· 1 shared Charles Stiles· 1 shared Christian BruefferiD· 1 shared Christopher J. GraseriD· 1 shared Christopher Mark WatsoniD· 1 shared Christos ProukakisiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperGenomics

Aaron M. WengerORCID

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Author profile →

2 papers

Recent·Most cited

H3K27M-driven hypertranscription leads to a new targetable dependency in diffuse midline gliomas

Sharmistha Pal, Heng Wang, Jacob Geisberg, Tasmia Mirza, Khushi Kohli, А. Ш. Назаретян, Truman Knowles, Christopher J. Graser, Kaitlyn Bootz, Olga Wójcikowska, Magda Bartyńska, Simon J. Boulton, Jayesh B. Majithiya, Helen Robinson, Graeme Smith, , Daphne Adele Haas-Kogan

This study identifies hypertranscription as a vulnerability in H3K27M-driven diffuse midline gliomas, showing ATR inhibition effectively targets this feature in preclinical models.

bioRxiv · May 15, 2026 · PreprintCancer Biology

SVCurator: A Crowdsourcing app to visualize evidence of structural variants for the human genome

Lesley M. Chapman, Noah Spies, Patrick Pai, Chun Shen Lim, Andrew W. Carroll, Giuseppe Narzisi, Christopher Mark Watson, Christos Proukakis, Wayne E. Clarke, Naoki Nariai, Eric T. Dawson, Garan Jones, Daniel J Blankenberg, Christian Brueffer, Chunlin Xiao, , Justin M. Zook

The paper introduces SVCurator, a crowdsourcing app for evaluating structural variants in the human genome, finding high concordance among curators and with existing benchmarks.

PLoS Computational Biology · Jun 19, 2020Peer-reviewedGenomics