SATB1 is a targetable modulator of JAK-STAT signaling and cytokines in human Treg and Tconv cells
Saskia Kolb, Leonie Diekmann, Elizabeth Daniel Lochert, Linda Warmuth, Julia Ritter, Gunter Schmidtke, Michael Weber, Markus Hoffmann, Markus List, Daniel Kotlarz, Isabelle Serr, Carolin Daniel, Dirk Hans Busch, Christian Schmidl, Kathrin Schumann
This study identifies SATB1 as a regulator of JAK-STAT signaling and cytokines in human Treg and Tconv cells, showing its potential as a target for CAR T cell therapy.
EMBO Reports · Jun 12, 2026Peer-reviewedImmunology