Linda Warmuth

The study identifies over 27,000 unique epitope-reactive TCRs from immunized mice, showing that TCR diversity is not constrained by germline VJ combinations but by combinatorial pairing of segments and CDR3 sequences.

This study identifies SATB1 as a regulator of JAK-STAT signaling and cytokines in human Treg and Tconv cells, showing its potential as a target for CAR T cell therapy.

This study shows that pentanoate, a microbial postbiotic, is metabolized to citrate, which influences T cell differentiation and anti-cancer CAR T cell efficacy through epigenetic mechanisms.