Localization of balanced chromosome translocation breakpoints by long-read sequencing on the Oxford Nanopore platform
Liang Hu, Fan Liang, Dehua Cheng, Zhiyuan Zhang, Guoliang Yu, Jianjun Zha, Yang Wang, Qi Xia, Daoli Yuan, Yue-Qiu Tan, Depeng Wang, Liang Yu, Ge Lin
This study uses Oxford Nanopore long-read sequencing to precisely localize breakpoints in balanced translocations and inversions, achieving single-base resolution for some cases.
Frontiers in Genetics · Jan 14, 2020Peer-reviewedGenetics