Author

H. Ebersbach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

K. M. Irvine· 2 shared A. D. Clouston· 1 shared A. Pettit· 1 shared A. Polyzou· 1 shared A. R. Pettit· 1 shared B. Genz· 1 shared B. Grimbacher· 1 shared B. Tse· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

K. M. Irvine

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3 papers

Recent·Most cited

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic metabolism to fuel growth.

S. Kesvari, J. Masson, M. Ferrari-Cestari, L.-G. Bodea, F. Nooru-Mohamed, B. Tse, K. Sokolowski, L. Batoon, O. Patkar, M. Sullivan, H. Ebersbach, C. Stutz, R. Parton, A. Pettit, D. Hume, K. M. Irvine

This study shows that CSF1 increases tissue macrophages and alters systemic metabolism, including glucose uptake and fat mobilization, with reversible effects on liver size and body composition.

bioRxiv · May 17, 2023 · PreprintImmunology

Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease

S. Keshvari, B. Genz, N. Teakle, M. Caruso, M. F. Cestari, O. L. Patkar, B. W. Tse, K. A. Sokolowski, H. Ebersbach, J. Jascur, K. P. MacDonald, G. Miller, G. A. Ramm, A. R. Pettit, A. D. Clouston, , K. M. Irvine

This study shows that CSF1-Fc treatment promotes liver regeneration and resolves advanced fibrosis in mice with chronic liver injury.

bioRxiv · Nov 7, 2021Immunology

ADA2 is a lysosomal DNase regulating the type-I interferon response

O. K. Greiner-Tollersrud, M. Krausz, E. Bartok, V. Boehler, H. Ebersbach, S. Baash, D. Guerini, G. Hartmann, K. Huebscher, G. Kochs, M. Marchant, A. Polyzou, J. Schepp, M. Seidl, C. R. Smulski, , M. Proietti

The paper identifies ADA2 as a lysosomal DNase that regulates the type-I interferon response by degrading cGAS/Sting-activating ligands in DADA2 patients.

bioRxiv · Jun 21, 2020 · PreprintImmunology